CBD Cheat-sheet: Cannabis and Diabetes

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Cannabis has been used by humans for millennia and only now are we really starting to find out the medical benefits of cannabis in treating known diseases and conditions.

Scientists at the Hebrew University of Jerusalem are very positive about the research they are doing on a cannabinoid known as cannabidiol ( CBD ). Led by Dr. Raphael Mechoulam, the scientist who isolated the CBD molecule, they believe it has huge potential in the treatment of diabetes using CBD. Further, they have reported CBD can be modified to fit different receptors found in our endocannabinoid system.

CBD is the non-psychoactive compound of cannabis and has been discovered to have many medicinal benefits, such as; anxiolytic, anti-inflammatory, antioxidant, anticonvulsant, and an antipsychotic agent. It is, therefore, a very effective treatment for depression, epilepsy, oxidative injury, vomiting, nausea, anxiety, schizophrenia, seizures, and insomnia. Most notably, CBD has been seen to assist in reducing cancerous tumors in people, with no real side-effects that traditional medicines provide.

Inflammation of tissues has long been known to play a key role in the development of resistance to insulin and type 2 diabetes. CBD has anti-inflammatory properties and in tests conducted on rats at the university have shown a great improvement in the regeneration of tissue in these dead areas.

“Unlike insulin and other existing medications for diabetes, CBD may actually suppress, reverse and perhaps cure the disease,” Dr. Daniel Rosenfeld –  Hebrew University of Jerusalem.

CBD is the non-psychoactive compound in cannabis, so it does not make you high. You are able to continue your daily activities without feeling “stoned”. It is non-addictive and non-toxic. Relatively few side effects have been found in patients using CBD. However sometimes in high doses ( 1,500 mg plus per day ), CBD users can experience tiredness, diarrhea, and a reduced appetite. CBD’s side effects are generally seen as mild and infrequent. According to Rosenfeld, the lack of side effects are also a major benefit for patients using CBD as a treatment.

CBD is found in the cannabis plant and especially found in Cannabis Sativa L. (hemp). Hemp is the non-psychoactive cousin of marijuana and is grown for its fiber and oils. Tetrahydrocannabinol ( THC ) is the compound found in cannabis that makes one “stoned” or “high”. Hemp generally contains less than 0.02% THC and is therefore not psychoactive and allows patients to treat themselves without the side effects of being high. CBD is being legally marketed and distributed in the United Kingdom as a dietary supplement and can be safe for use by both adults and children.

There are quite a few methods of using CBD as a treatment and with the wide variety of products available, patients can choose what best suits their needs. Mouth Sprays, topical balms through to concentrated CBD vape liquids, amongst others allow patients to absorb the medical benefits of the CBD compound, allowing treatment to begin almost immediately. Best is using CBD over a period of time after seeking out sound professional advice.

CLINICAL STUDIES: RESOURCES

  1. The impact of marijuana use on glucose, insulin, and insulin resistance among US adults
  2. CBD attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy
  3. CBD lowers incidence of diabetes in non-obese diabetic mice
  4. Neuroprotective and blood-retinal barrier-preserving effects of CBD in experimental diabetes
  5. Cannabidiol arrests onset of autoimmune diabetes in NOD mice
  6. Diabetic retinopathy: Role of inflammation and potential therapies for anti-inflammation
  7. Cannabinoids alter endothelial function in the Zucker rat model of type 2 diabetes
  8. The endocannabinoid system in obesity and type 2 diabetes
  9. Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes
  10. The endocannabinoid system and plant-derived cannabinoids in diabetes and diabetic complications
  11. Cannabinoid-mediated modulation of neuropathic pain and microglial accumulation in a model of murine type I diabetic peripheral neuropathic pain
  12. Biochemical and immunohistochemical changes in delta-9-tetrahydrocannabinol-treated type 2 diabetic rats
  13. Efficacy and Safety of CBD and THC-V on Glycemic and Lipid Parameters in Patients With Type 2 Diabetes

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